Product References
Intrinsic B cell TLR-BCR linked coengagement induces class-switched, hypermutated, neutralizing antibody responses in absence of T cells.
Science advances
Rivera CE,Zhou Y,Chupp DP,Yan H,Fisher AD,Simon R,Zan H,Xu Z,Casali P
11-4204-82 was used in Flow Cytometry to show that B cell TLR4-BCR coengagement by NP-LPS or TLR5-BCR coengagement by Salmonella flagellin induces mature antibody responses to NP and flagellin in Tcrβ-/-Tcrδ-/- and NSG/B mice.
Fri Apr 28 00:00:00 UTC 2023
53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis.
Nature cell biology
Mirman Z,Sasi NK,King A,Chapman JR,de Lange T
11-4204-82 was used in Flow cytometry/Cell sorting to investigate if BRCA1-deficient cells, CST-Polα-primase is the major effector of shieldin-dependent double-strand breaks processing.
Sat Jan 01 00:00:00 UTC 2022
Rad52 mediates class-switch DNA recombination to IgD.
Nature communications
Xu Y,Zhou H,Post G,Zan H,Casali P
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Mon Feb 21 00:00:00 UTC 2022
Orange-derived and dexamethasone-encapsulated extracellular vesicles reduced proteinuria and alleviated pathological lesions in IgA nephropathy by targeting intestinal lymphocytes.
Frontiers in immunology
Zhang W,Yuan Y,Li X,Luo J,Zhou Z,Yu L,Wang G
11-4204-82 was used in Flow cytometry/Cell sorting to develop a cost-effective, biofriendly EVs-based glucocorticoid strategy for IgAN.
Tue Sep 20 00:00:00 UTC 2022
Fibroblastic reticular cell lineage convergence in Peyer's patches governs intestinal immunity.
Nature immunology
Prados A,Onder L,Cheng HW,Mörbe U,Lütge M,Gil-Cruz C,Perez-Shibayama C,Koliaraki V,Ludewig B,Kollias G
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Thu Apr 01 00:00:00 UTC 2021
Functional human IgA targets a conserved site on malaria sporozoites.
Science translational medicine
Tan J,Cho H,Pholcharee T,Pereira LS,Doumbo S,Doumtabe D,Flynn BJ,Schön A,Kanatani S,Aylor SO,Oyen D,Vistein R,Wang L,Dillon M,Skinner J,Peterson M,Li S,Idris AH,Molina-Cruz A,Zhao M,Olano LR,Lee PJ,Roth A,Sinnis P,Barillas-Mury C,Kayentao K,Ongoiba A,Francica JR,Traore B,Wilson IA,Seder RA,Crompton PD
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Wed Jun 23 00:00:00 UTC 2021
TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA.
JCI insight
Platt JL,de Mattos Barbosa MG,Huynh D,Lefferts AR,Katta J,Kharas C,Freddolino P,Bassis CM,Wobus C,Geha R,Bram R,Nunez G,Kamada N,Cascalho M
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Thu Jul 22 00:00:00 UTC 2021
Glycan-based shaping of the microbiota during primate evolution.
eLife
Singh S,Bastos-Amador P,Thompson JA,Truglio M,Yilmaz B,Cardoso S,Sobral D,Soares MP
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Wed May 19 00:00:00 UTC 2021
Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation.
Cell host & microbe
Yang C,Mogno I,Contijoch EJ,Borgerding JN,Aggarwala V,Li Z,Siu S,Grasset EK,Helmus DS,Dubinsky MC,Mehandru S,Cerutti A,Faith JJ
11-4204 was used in Immunohistochemistry to assess the IgA-inducing capacity of a diverse set of human gut microbial strains by monocolonizing mice with each strain.
Wed Mar 11 00:00:00 UTC 2020
Functional Radiogenetic Profiling Implicates ERCC6L2 in Non-homologous End Joining.
Cell reports
Francica P,Mutlu M,Blomen VA,Oliveira C,Nowicka Z,Trenner A,Gerhards NM,Bouwman P,Stickel E,Hekkelman ML,Lingg L,Klebic I,van de Ven M,de Korte-Grimmerink R,Howald D,Jonkers J,Sartori AA,Fendler W,Chapman JR,Brummelkamp T,Rottenberg S
11-4204 was used in Flow cytometry/Cell sorting to show that ERCC6L2 contributes to non-homologous end joining (NHEJ), and it may exert this function through interactions with SFPQ.
Tue Aug 25 00:00:00 UTC 2020
Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity.
Immunity
Martínez-López M,Iborra S,Conde-Garrosa R,Mastrangelo A,Danne C,Mann ER,Reid DM,Gaboriau-Routhiau V,Chaparro M,Lorenzo MP,Minnerup L,Saz-Leal P,Slack E,Kemp B,Gisbert JP,Dzionek A,Robinson MJ,Rupérez FJ,Cerf-Bensussan N,Brown GD,Bernardo D,LeibundGut-Landmann S,Sancho D
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Tue Feb 19 00:00:00 UTC 2019
CHK1 dosage in germinal center B cells controls humoral immunity.
Cell death and differentiation
Schoeler K,Jakic B,Heppke J,Soratroi C,Aufschnaiter A,Hermann-Kleiter N,Villunger A,Labi V
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Sun Dec 01 00:00:00 UTC 2019
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases.
Nature communications
Tran HQ,Ley RE,Gewirtz AT,Chassaing B
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Wed Dec 11 00:00:00 UTC 2019
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Nature communications
Ramakrishnan SK,Zhang H,Ma X,Jung I,Schwartz AJ,Triner D,Devenport SN,Das NK,Xue X,Zeng MY,Hu Y,Mortensen RM,Greenson JK,Cascalho M,Wobus CE,Colacino JA,Nunez G,Rui L,Shah YM
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Fri Feb 08 00:00:00 UTC 2019
Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.
Cellular and molecular gastroenterology and hepatology
Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Western Blot
Mon Apr 29 00:00:00 UTC 2019
Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.
Cellular and molecular gastroenterology and hepatology
Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Western Blot
Mon Apr 29 00:00:00 UTC 2019
53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ.
Nature
Ghezraoui H,Oliveira C,Becker JR,Bilham K,Moralli D,Anzilotti C,Fischer R,Deobagkar-Lele M,Sanchiz-Calvo M,Fueyo-Marcos E,Bonham S,Kessler BM,Rottenberg S,Cornall RJ,Green CM,Chapman JR
11-4204 was used in Flow cytometry/Cell sorting to conclude that the 53BP1 pathway therefore comprises distinct double-strand break repair activities within chromatin and single-stranded DNA compartments, which explains both the immunological differences between 53bp1- and Rev7- deficient mice and the context specificity of the pathway.
Wed Aug 01 00:00:00 UTC 2018
Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Cell
Grohmann M,Wiede F,Dodd GT,Gurzov EN,Ooi GJ,Butt T,Rasmiena AA,Kaur S,Gulati T,Goh PK,Treloar AE,Archer S,Brown WA,Muller M,Watt MJ,Ohara O,McLean CA,Tiganis T
11-4204-82 was used in Flow Cytometry to reveal how obesity-associated hepatic oxidative stress can independently contribute to the pathogenesis of non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.
Thu Nov 15 00:00:00 UTC 2018
Commensals Suppress Intestinal Epithelial Cell Retinoic Acid Synthesis to Regulate Interleukin-22 Activity and Prevent Microbial Dysbiosis.
Immunity
Grizotte-Lake M,Zhong G,Duncan K,Kirkwood J,Iyer N,Smolenski I,Isoherranen N,Vaishnava S
11-4204 was used in Flow cytometry/Cell sorting to define a regulatory circuit wherein bacterial regulation of IEC-intrinsic RA synthesis protects microbial communities in the gut from excessive immune activity, achieving a balance that prevents colonization by enteric pathogens.
Tue Dec 18 00:00:00 UTC 2018
Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production.
International journal of molecular sciences
Tsuji R,Ikado K,Fujiwara D
11-4204 was used in Flow cytometry/Cell sorting to investigate immune-stimulatory activity of lignin-rich enzyme lignin in vivo.
Tue Dec 26 00:00:00 UTC 2017
Tetraspanin CD37 protects against the development of B cell lymphoma.
The Journal of clinical investigation
de Winde CM,Veenbergen S,Young KH,Xu-Monette ZY,Wang XX,Xia Y,Jabbar KJ,van den Brand M,van der Schaaf A,Elfrink S,van Houdt IS,Gijbels MJ,van de Loo FA,Bennink MB,Hebeda KM,Groenen PJ,van Krieken JH,Figdor CG,van Spriel AB
11-4204 was used in Flow cytometry/Cell sorting to show that CD37 deficiency drives B cell lymphomagenesis through constitutive activation of the IL-6 pathway, highlighting a possible therapeutic intervention.
Mon Feb 01 00:00:00 UTC 2016
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization.
Nature communications
Bemark M,Hazanov H,Strömberg A,Komban R,Holmqvist J,Köster S,Mattsson J,Sikora P,Mehr R,Lycke NY
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Tue Sep 06 00:00:00 UTC 2016
Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization.
Nature communications
Bemark M,Hazanov H,Strömberg A,Komban R,Holmqvist J,Köster S,Mattsson J,Sikora P,Mehr R,Lycke NY
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Tue Sep 06 00:00:00 UTC 2016
Bombesin improves adaptive immunity of the salivary gland during parenteral nutrition.
JPEN. Journal of parenteral and enteral nutrition
Pierre JF,Heneghan AF,Wang X,Roenneburg DA,Groblewski GE,Kudsk KA
11420482 was used in immunohistochemistry - paraffin section to test if bombesin stimulates parotid and salivary gland IgA levels, T lymphocytes, and IgA plasma cell counts
Sun Feb 01 00:00:00 UTC 2015
R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Kim MS,Kim TS
Published figure using IgA monoclonal antibody (Product # 11-4204-82) in Flow Cytometry
Wed May 01 00:00:00 UTC 2013
