Product References
Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response.
Cell reports
Hu Q,Xu T,Zhang M,Zhang H,Liu Y,Li HB,Chen C,Zheng J,Zhang Z,Li F,Shen N,Zhang W,Melnick A,Huang C
13-5993-82 was used in Flow cytometry/Cell sorting to reveal that differential dynamics of Bach2 protein and transcripts in activated B cells control their cell-fate outcomes and imprint the fates of their descendant effector cells.
Tue Jul 05 00:00:00 UTC 2022
Ddb1 Is Essential for the Expansion of CD4+ Helper T Cells by Regulating Cell Cycle Progression and Cell Death.
Frontiers in immunology
Yang L,Chen W,Li L,Xiao Y,Fan S,Zhang Q,Xia T,Li M,Hong Y,Zhao T,Li Q,Liu WH,Xiao N
Published figure using IgD monoclonal antibody (Product # 13-5993-82) in Flow Cytometry
Mon Dec 20 00:00:00 UTC 2021
A pathogen-like antigen-based vaccine confers immune protection against SARS-CoV-2 in non-human primates.
Cell reports. Medicine
Guo C,Peng Y,Lin L,Pan X,Fang M,Zhao Y,Bao K,Li R,Han J,Chen J,Song TZ,Feng XL,Zhou Y,Zhao G,Zhang L,Zheng Y,Zhu P,Hang H,Zhang L,Hua Z,Deng H,Hou B
13-5993-82 was used in Immunohistochemistry to demonstrate that the viral clearance is accelerated in vaccinated animals. In addition, the PLA-based vaccine induces a T helper 1 (Th1)-oriented response and a durable memory, supporting its potential for further clinical development.
Tue Nov 16 00:00:00 UTC 2021
Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA.
Immunity
Soni C,Perez OA,Voss WN,Pucella JN,Serpas L,Mehl J,Ching KL,Goike J,Georgiou G,Ippolito GC,Sisirak V,Reizis B
13-5993-82 was used in Flow Cytometry to establish extrafollicular B cell differentiation into short-lived AFCs as a key mechanism of anti-DNA autoreactivity and reveal a major contribution of pDCs, endosomal Toll-like receptors (TLRs), and IFN-I to this pathway.
Tue Jun 16 00:00:00 UTC 2020
T-B Lymphocyte Interactions Promote Type 1 Diabetes Independently of SLAM-Associated Protein.
Journal of immunology (Baltimore, Md. : 1950)
Bonami RH,Nyhoff LE,McNitt DH,Hulbert C,Felton JL,Kendall PL,Thomas JW
13-5993-82 was used in Flow Cytometry to understand how fully developed T follicular helper cells contribute to different autoimmune processes, investigating the role of signaling lymphocytic activation molecule-associated protein in type 1 diabetes and autoantibody-mediated arthritis.
Tue Dec 15 00:00:00 UTC 2020
STING couples with PI3K to regulate actin reorganization during BCR activation.
Science advances
Jing Y,Dai X,Yang L,Kang D,Jiang P,Li N,Cheng J,Li J,Miller H,Ren B,Gong Q,Yin W,Liu Z,Mattila PK,Ning Q,Sun J,Yu B,Liu C
13-5993 was used in Immunohistochemistry to study the effect of STING (stimulator of interferon genes) deficiency on B cell development, differentiation, and BCR signalling.
Wed Apr 01 00:00:00 UTC 2020
Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice.
Cell reports
Matsumura T,Ikebe T,Arikawa K,Hosokawa M,Aiko M,Iguchi A,Togashi I,Kai S,Ohara S,Ohara N,Ohnishi M,Watanabe H,Kobayashi K,Takeyama H,Yamasaki S,Takahashi Y,Ato M
13-5993-82 was used in Magnetic cell separation to show IFN-γ-producing immature myeloid cells can provide protection to mice in invasive group A Streptococcus infection.
Tue Apr 09 00:00:00 UTC 2019
Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b.
Nature communications
Cho S,Lee HM,Yu IS,Choi YS,Huang HY,Hashemifar SS,Lin LL,Chen MC,Afanasiev ND,Khan AA,Lin SW,Rudensky AY,Crotty S,Lu LF
Published figure using IgD monoclonal antibody (Product # 13-5993-82) in Immunofluorescence
Mon Jul 16 00:00:00 UTC 2018
Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice.
Cellular and molecular life sciences : CMLS
van Nieuwenhuijze A,Dooley J,Humblet-Baron S,Sreenivasan J,Koenders M,Schlenner SM,Linterman M,Liston A
13599382 was used in flow cytometry to evaluate miR-29a in B cells as a potential therapeutic target in arthritis
Thu Jun 01 00:00:00 UTC 2017
IgD attenuates the IgM-induced anergy response in transitional and mature B cells.
Nature communications
Sabouri Z,Perotti S,Spierings E,Humburg P,Yabas M,Bergmann H,Horikawa K,Roots C,Lambe S,Young C,Andrews TD,Field M,Enders A,Reed JH,Goodnow CC
13-5993 was used in Flow cytometry/Cell sorting to define the RNA landscape of the in vivo anergy response, comprising 220 induced sequences including a core set of 97.
Thu Nov 10 00:00:00 UTC 2016
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-5993 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 UTC 2015
Distinct germinal center selection at local sites shapes memory B cell response to viral escape.
The Journal of experimental medicine
Adachi Y,Onodera T,Yamada Y,Daio R,Tsuiji M,Inoue T,Kobayashi K,Kurosaki T,Ato M,Takahashi Y
13-5993 was used in Flow cytometry/Cell sorting to investigate the cellular events dictating the cross-reactive memory B cell responses, showing that distinct germinal center selection at local sites shapes response to viral escape.
Mon Sep 21 00:00:00 UTC 2015
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
The Journal of experimental medicine
Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC
13-5993 was used in Flow cytometry/Cell sorting to reveal a potentially critical role for the MEK5-ERK5 MAP kinase signalling pathway in BAFF-induced mature B cell survival and homeostatic maintenance of B2 cell numbers.
Mon Jun 01 00:00:00 UTC 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using IgD monoclonal antibody (Product # 13-5993-82) in Flow Cytometry
Tue Sep 01 00:00:00 UTC 2015
BILL-cadherin/cadherin-17 contributes to the survival of memory B cells.
PloS one
Funakoshi S,Shimizu T,Numata O,Ato M,Melchers F,Ohnishi K
Published figure using IgD monoclonal antibody (Product # 13-5993-82) in Flow Cytometry
Wed Sep 16 00:00:00 UTC 2015
Immature B Cell Egress from Bone Marrow Is SOCS3 Independent.
PloS one
Nadrah K,Beck TC,Pereira JP
13-5993 was used in Flow cytometry/Cell sorting to investigate the role of suppressor of cytokine signaling 3 (SOCS3) in mediating immature B cell egress from the bone marrow, and other biological processes controlled by CXCR4 signalling.
Fri May 06 00:00:00 UTC 2016
Essential role for autophagy in the maintenance of immunological memory against influenza infection.
Nature medicine
Chen M,Hong MJ,Sun H,Wang L,Shi X,Gilbert BE,Corry DB,Kheradmand F,Wang J
13-5993 was used in Flow cytometry/Cell sorting to demonstrate autophagy is essential for the survival of virus-specific memory B cells and maintenance of protective antibody responses.
Thu May 01 00:00:00 UTC 2014
Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice.
Journal of immunology (Baltimore, Md. : 1950)
Hua Z,Gross AJ,Lamagna C,Ramos-Hernández N,Scapini P,Ji M,Shao H,Lowell CA,Hou B,DeFranco AL
13-5993 was used in Immunohistochemistry to use a conditional allele of Myd88 to determine whether the autoimmunity of Lyn(-/-) mice is dependent on TLR/MyD88 signaling in B cells and/or in dendritic cells (DCs).
Sat Feb 01 00:00:00 UTC 2014
Loss of an Igκ gene enhancer in mature B cells results in rapid gene silencing and partial reversible dedifferentiation.
Molecular and cellular biology
Zhou X,Xiang Y,Ding X,Garrard WT
Published figure using IgD monoclonal antibody (Product # 13-5993-82) in Flow Cytometry
Wed May 01 00:00:00 UTC 2013
The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells.
Molecular immunology
Aragon IV,Barrington RA,Jackowski S,Mori K,Brewer JW
13-5993 was used in Flow cytometry/Cell sorting to demonstrate that a specialised B cell UPR relies exclusively on the IRE1-XBP1 pathway to remodel the ER and expand secretory capacity.
Sun Jul 01 00:00:00 UTC 2012
ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes.
Nature immunology
Yabas M,Teh CE,Frankenreiter S,Lal D,Roots CM,Whittle B,Andrews DT,Zhang Y,Teoh NC,Sprent J,Tze LE,Kucharska EM,Kofler J,Farell GC,Bröer S,Goodnow CC,Enders A
13-5993 was used in Flow cytometry/Cell sorting to study the connection between phospholipid transport and B lymphocyte function.
Sun May 01 00:00:00 UTC 2011
Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants.
The Journal of experimental medicine
Purtha WE,Tedder TF,Johnson S,Bhattacharya D,Diamond MS
13-5993 was used in Flow cytometry/Cell sorting to study the ability of memory B cells to target mutant viral epitopes.
Mon Dec 19 00:00:00 UTC 2011
Magnetic-based purification of untouched mouse germinal center B cells for ex vivo manipulation and biochemical analysis.
Nature protocols
Cato MH,Yau IW,Rickert RC
13-5993 was used in Magnetic cell separation to provide a protocol for a novel magnetic bead separation scheme for the purification of mature B cells for biochemical assessment.
Thu Jun 09 00:00:00 UTC 2011
Role of central leptin signaling in the starvation-induced alteration of B-cell development.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Tanaka M,Suganami T,Kim-Saijo M,Toda C,Tsuiji M,Ochi K,Kamei Y,Minokoshi Y,Ogawa Y
13-5993 was used in Flow cytometry/Cell sorting to show that the alteration of B-cell development in the bone marrow of fasted and obese mice can be reversed by central leptin administration.
Wed Jun 08 00:00:00 UTC 2011
Mutation of the BAFF furin cleavage site impairs B-cell homeostasis and antibody responses.
European journal of immunology
Bossen C,Tardivel A,Willen L,Fletcher CA,Perroud M,Beermann F,Rolink AG,Scott ML,Mackay F,Schneider P
13-5993 was used in Flow cytometry/Cell sorting to study the functional importance of B-cell-activating factor of the TNF family processing by proteolytic cleavage.
Tue Mar 01 00:00:00 UTC 2011
Use of a virus-encoded enzymatic marker reveals that a stable fraction of memory B cells expresses latency-associated nuclear antigen throughout chronic gammaherpesvirus infection.
Journal of virology
Nealy MS,Coleman CB,Li H,Tibbetts SA
13-5993 was used in Flow cytometry/Cell sorting to investigate the expression of LANA/EBNA-1 in individual B-cell subsets through the course of chronic gammaherpesvirus infection, showing that a stable fraction of memory B cells expresses LANA.
Sun Aug 01 00:00:00 UTC 2010
Impaired apoptotic cell clearance in the germinal center by Mer-deficient tingible body macrophages leads to enhanced antibody-forming cell and germinal center responses.
Journal of immunology (Baltimore, Md. : 1950)
Rahman ZS,Shao WH,Khan TN,Zhen Y,Cohen PL
13-5993 was used in Flow cytometry/Cell sorting to demonstrate a critical role for Mer in GC apoptotic cell clearance by TBMΦs.
Mon Nov 15 00:00:00 UTC 2010
Unique requirements for reactivation of virus-specific memory B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Weisel FJ,Appelt UK,Schneider AM,Horlitz JU,van Rooijen N,Korner H,Mach M,Winkler TH
13-5993 was used in Immunofluorescence on frozen tissues to study how the reactivation of memory B lymphocytes may occur inside lymphoid follicles, and how this activation has virus-specific requirements.
Fri Oct 01 00:00:00 UTC 2010
Type I IFN-induced, NKT cell-mediated negative control of CD8 T cell priming by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Bochtler P,Kröger A,Schirmbeck R,Reimann J
13-5993-82 was used in Flow cytometry/Cell sorting to investigated the negative effect of type I IFN (IFN-I) on the priming of specific CD8 T cell immunity.
Fri Aug 01 00:00:00 UTC 2008
Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination.
The Journal of experimental medicine
Bates JG,Cado D,Nolla H,Schlissel MS
13-5993 was used in Flow cytometry/Cell sorting to study the importance of the chromosomal positioning of a VH gene segment in determining its activation and inactivation as a substrate for V(D)J recombination.
Mon Dec 24 00:00:00 UTC 2007
c-Myb is critical for B cell development and maintenance of follicular B cells.
Immunity
Thomas MD,Kremer CS,Ravichandran KS,Rajewsky K,Bender TP
13-5993 was used in Flow cytometry/Cell sorting to demonstrate that loss of Myb causes a partial block during B-cell development, reducing output of new B-cells.
Thu Sep 01 00:00:00 UTC 2005
B1b lymphocytes confer T cell-independent long-lasting immunity.
Immunity
Alugupalli KR,Leong JM,Woodland RT,Muramatsu M,Honjo T,Gerstein RM
13-5993 was used in Flow cytometry/Cell sorting to demonstrate that B1b lymphocytes provide long-lasting T cell-independent IgM memory and a successful resolution of Borrelia hermsiibacteremia in mice.
Wed Sep 01 00:00:00 UTC 2004
