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14-3-3 Sigma/Stratifin Monoclonal Antibody (CPTC-SFN-2)

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抗体检测数据 (4)

14-3-3 Sigma/Stratifin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

14-3-3 Sigma/Stratifin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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14-3-3 Sigma/Stratifin Antibody (2810-MSM1-P1ABX) in IHC (P)

Immunohistochemistry analysis of formalin-fixed, paraffin-embedded human Skin stained with 14-3-3 Sigma/Stratifin Monoclonal Antibody (Product # 2810-MSM1-P1ABX).

14-3-3 Sigma/Stratifin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

14-3-3 Sigma/Stratifin Antibody in Western Blot (WB)

14-3-3 Sigma/Stratifin Antibody in Peptide array (ARRAY)

14-3-3 Sigma/Stratifin Antibody in SDS-PAGE (SDS-PAGE)

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14-3-3 Sigma/Stratifin Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of formalin-fixed, paraffin-embedded human Skin stained with 14-3-3 Sigma/Stratifin Monoclonal Antibody (Product # 2810-MSM1-P1ABX).

14-3-3 Sigma/Stratifin Antibody in Western Blot (WB) — Western Blot analysis of Human PC-3 cell lysate using 14-3-3 Sigma, Stratifin Monoclonal Antibody (Product # 2810-MSM1-P1ABX).

14-3-3 Sigma/Stratifin Antibody in Peptide array (ARRAY) — Analysis of Protein Array containing more than 19,000 full-length human proteins 14-3-3 Sigma, Stratifin Monoclonal Antibody (Product # 2810-MSM1-P1ABX). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

14-3-3 Sigma/Stratifin Antibody in SDS-PAGE (SDS-PAGE) — SDS-PAGE Analyis Purified 14-3-3 Sigma, Stratifin Monoclonal Antibody (Product # 2810-MSM1-P1ABX). Confirmation of Purity and Integrity of Antibody.

产品信息

2810-MSM1-P1ABX

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-2 µg/mL

-

免疫组化（石蜡） (IHC (P))

1-2 µg/mL

-

肽阵列 (Array)

Assay-dependent

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

CPTC-SFN-2

抗原

Recombinant human full-length SFN protein

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C or -80°C if preferred

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

靶标信息

This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 14-3-3 protein sigma; 14-3-3 sigma; 14-3-3sigma; Epithelial cell marker protein 1; HGNC:10773; Stratifin

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基因别名: HME1; SFN; YWHAS

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UniProt ID: (Human) P31947

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Entrez Gene ID: (Human) 2810

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protein binding protein kinase C inhibitor activity protein kinase binding protein domain specific binding phosphoprotein binding cadherin binding involved in cell-cell adhesion scaffold/adaptor protein

regulation of cyclin-dependent protein serine/threonine kinase activity release of cytochrome c from mitochondria keratinocyte development negative regulation of protein kinase activity DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest signal transduction intrinsic apoptotic signaling pathway in response to DNA damage regulation of epidermal cell division negative regulation of keratinocyte proliferation positive regulation of cell growth keratinization negative regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of epidermal cell differentiation positive regulation of protein export from nucleus membrane organization establishment of skin barrier negative regulation of protein serine/threonine kinase activity cell-cell adhesion positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway