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14-3-3 eta Antibody (PA5-75298) in IHC (P)
Immunohistochemistry analysis of 14-3-3 eta in paraffin-embedded human breast carcinoma tissue (cytoplasmic and nucleus staining) and negative control (right, with PBS only). Samples were incubated with 14-3-3 eta polyclonal antibody (Product # PA5-75298) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
产品信息
PA5-75298
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 50-100 of Human 14-3-3 eta.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719026
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 14-3-3 eta; 14-3-3 protein eta; 14-3-3 protein eta-subtype; 1433F; Protein AS1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; YWHA114-3-3 eta
基因别名: 14-3-3e; YWHA1; YWHAH
UniProt ID: (Human) Q04917, (Rat) P68511, (Mouse) P68510
Entrez Gene ID: (Human) 7533, (Rat) 25576, (Mouse) 22629
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
substantia nigra development
glucocorticoid receptor signaling pathway
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
membrane organization
membrane depolarization during action potential
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of sodium ion transmembrane transporter activity
biological_process
cytoskeleton organization
regulation of mitotic nuclear division
negative regulation of apoptotic process
