Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
2-hydroxyisobutyryl-Histone Macro-H2A.1 (Lys9) Polyclonal Antibody
图: 1 / 1
2-hydroxyisobutyryl-Histone Macro-H2A.1 (Lys9) Antibody (PA5-112463) in WB
Western Blot analysis of 2-hydroxyisobutyryl-Histone Macro-H2A.1 (Lys9) in A549 whole cell lysate using a 2-hydroxyisobutyryl-Histone Macro-H2A.1 (Lys9) polyclonal antibody (Product # PA5-112463) at a concentration of 0.44 µg/ml. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000.
产品信息
PA5-112463
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide sequence around site of 2-hydroxyisobutyryl-Lys (9) derived from Human Histone H2A type 1
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2867198
靶标信息
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Core histone macro-H2A.1; H2A histone family, member Y; H2A/y; Histone H2A.y; Histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; Medulloblastoma antigen MU-MB-50.205
基因别名: H2A.y; H2A/y; H2AF12M; H2AFY; MACROH2A1; MACROH2A1.1; macroH2A1.2; mH2A1
UniProt ID: (Human) O75367
Entrez Gene ID: (Human) 9555
rDNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
protein binding
double-stranded methylated DNA binding
enzyme binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
chromatin DNA binding
nucleosomal DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
histone
negative regulation of transcription from RNA polymerase II promoter
regulation of cell growth
nucleosome assembly
chromatin silencing
dosage compensation
covalent chromatin modification
regulation of lipid metabolic process
negative regulation of histone phosphorylation
positive regulation of maintenance of mitotic sister chromatid cohesion
regulation of gene expression, epigenetic
positive regulation of keratinocyte differentiation
negative regulation of gene expression, epigenetic
positive regulation of gene expression, epigenetic
negative regulation of histone H3-K4 methylation
negative regulation of histone H3-K27 methylation
regulation of chromatin silencing at rDNA
establishment of protein localization to chromatin
negative regulation of protein serine/threonine kinase activity
negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
negative regulation of cell cycle G2/M phase transition
negative regulation of protein localization to chromosome, telomeric region
