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AADAT Antibody (PA5-88974) in IHC (P)
Immunohistochemistry analysis of AADAT in paraffin-embedded human liver. Samples were incubated with AADAT Polyclonal antibody (Product # PA5-88974) using a dilution of 1:200 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-88974
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_0012736111)
偶联物
形式
Liquid
浓度
1.38 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805265
产品详细信息
Immunogen sequence: PKSMISLAGG LPNPNMFPFK TAVITVENGK TIQFGEEMMK RALQYSPSAG IPELLSWLKQ LQIKLHNPPT IHYPPSQGQM DLCVTSGSQQ GLCKVFEMII NPGDNVLLDE PAYSGTLQSL HPLGCNIINV ASDESGIVPD SLRDILSRWK PEDAKNPQKN TPKFLYTVPN GNNPTGNSLT SERKKEIYEL ARKYDFLIIE DDPYYFLQFN KFRVPTFLSM DVDGRVIRAD SFSKIISSGL RIGFLTGPKP LIERVILHIQ VSTLHPSTFN QLMISQLLHE WGEEGFMAHV DRVIDFYSNQ KDAILAAADK WLTGLAEWHV PAAGMFLWIK VKGINDVKEL IEEKAVKMGV LMLPGNAFYV DSSAPSPYLR ASFSSASPEQ MDVAFQVLAQ LIKESL; Positive Samples: Mouse liver, Rat kidney; Cellular Location: Mitochondrion
靶标信息
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; AadAT; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; KAT/AadAT; kynurenine aminotransferase 2; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; kynurenine--oxoglutarate; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; L kynurenine/alpha aminoadipate aminotransferase; Methionine--glyoxylate transaminase AADAT
基因别名: AADAT; Aadt; AI875679; KAT2; KATII; KYAT2; mKat-2
UniProt ID: (Human) Q8N5Z0, (Mouse) Q9WVM8, (Rat) Q64602
Entrez Gene ID: (Human) 51166, (Mouse) 23923, (Rat) 29416
