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产品信息
PA5-92379
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 29-300 of human GABA transaminase (GABA transaminase (ABAT)) (NP_0011209201)
偶联物
形式
Liquid
浓度
1.04 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806464
产品详细信息
Immunogen sequence: SQAAAKVDVE FDYDGPLMKT EVPGPRSQEL MKQLNIIQNA EAVHFFCNYE ESRGNYLVDV DGNRMLDLYS QISSVPIGYS HPALLKLIQQ PQNASMFVNR PALGILPPEN FVEKLRQSLL SVAPKGMSQL ITMACGSCSN ENALKTIFMW YRSKERGQRG FSQEELETCM INQAPGCPDY SILSFMGAFH GRTMGCLATT HSKAIHKIDI PSFDWPIAPF PRLKYPLEEF VKENQQEEAR CLEEVEDLIV KYRKKKKTVA GIIVEPIQSE GG; Positive Samples: SW480, A375, Mouse liver, Mouse kidney, Mouse brain; Cellular Location: Mitochondrion matrix
靶标信息
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: (S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase, mitochondrial; 4-aminobutyrate transaminase; beta-AlaAT I; beta-alanine oxoglutarate aminotransferase; FLJ17813; FLJ30272; GABA aminotransferase; GABA AT; GABA T; GABA transaminase; GABA transferase; GABA-AT; GABA-T; Gamma-amino-N-butyrate transaminase; hCG1984265; L AIBAT; L-AIBAT
基因别名: 9630038C02Rik; ABAT; AI255750; beta-AlaAT; ENSMUSG00000051226; GABA-AT; Gabaat; GABAT; Gm9851; I54; Laibat; NPD009; X61497
UniProt ID: (Human) P80404, (Rat) P50554, (Mouse) P61922
Entrez Gene ID: (Human) 18, (Rat) 81632, (Mouse) 268860
4-aminobutyrate transaminase activity
pyridoxal phosphate binding
succinate-semialdehyde dehydrogenase binding
protein homodimerization activity
metal ion binding
(S)-3-amino-2-methylpropionate transaminase activity
iron-sulfur cluster binding
catalytic activity
transaminase activity
transferase activity
transaminase
response to hypoxia
aging
copulation
locomotory behavior
gamma-aminobutyric acid biosynthetic process
gamma-aminobutyric acid catabolic process
response to iron ion
negative regulation of gamma-aminobutyric acid secretion
cerebellum development
positive regulation of heat generation
positive regulation of insulin secretion
negative regulation of dopamine secretion
response to nicotine
exploration behavior
neurotransmitter catabolic process
response to drug
response to ethanol
negative regulation of blood pressure
positive regulation of dopamine metabolic process
behavioral response to cocaine
positive regulation of uterine smooth muscle contraction
negative regulation of platelet aggregation
positive regulation of inhibitory postsynaptic potential
positive regulation of prolactin secretion
positive regulation of aspartate secretion
response to cocaine
gamma-aminobutyric acid metabolic process
