Invitrogen

ABCB9 Polyclonal Antibody

ABCB9 Antibody in Immunocytochemistry (ICC/IF)

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ABCB9 Antibody (PA5-65139) in ICC/IF

Immunofluorescent staining of ABCB9 in human cell line U-2 OS shows localization to vesicles. Samples were probed using an ABCB9 Polyclonal Antibody (Product # PA5-65139).

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产品信息

PA5-65139

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human ABCB9. Recombinant protein control fragment (Product #RP-105896).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2664863

产品详细信息

Immunogen sequence: GGLYAKLVQRQ MLGLQPAADF TAGHNEPVAN GSHKA

Highest antigen sequence identity to the following orthologs - mouse 69%, rat 72%.

靶标信息

The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3' of the DNA lesion while the ERCC1 / XPF complex makes the 5' incision. ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ABC transporter 9 protein; ABC-type oligopeptide transporter ABCB9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; TAP-like protein; TAPL

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基因别名: ABCB9; EST122234; KIAA1520; TAPL

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UniProt ID: (Human) Q9NP78

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Entrez Gene ID: (Human) 23457

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功能

protein binding ATP binding oligopeptide-transporting ATPase activity peptide-transporting ATPase activity substrate-specific transmembrane transporter activity protein homodimerization activity ATP-binding cassette (ABC) transporter

参与通路

antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent positive regulation of antigen processing and presentation of peptide antigen via MHC class I protein transport peptide transport oligopeptide transmembrane transport transmembrane transport