Invitrogen

ABCG8 Polyclonal Antibody

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ABCG8 Antibody (PA1-16798) in WB

Western blot analysis of ABCG8 in mouse small intestine. Samples were incubated in ABCG8 polyclonal antibody (Product # PA1-16798) using a dilution of 2 µg/mL followed by an anti-rabbit HRP secondary antibody. Separated on a 7.5% gel by SDS-PAGE and transferred to PVDF membrane. Detection: chemiluminescence.

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产品信息

PA1-16798

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:250-1:500

免疫细胞化学 (ICC/IF)

1:250

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide from the n-terminal region of human ABCG8 protein.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

tris citrate, pH 7-8

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2257680

产品详细信息

Longer exposure times are needed to visualize the wild type ABCG8.

靶标信息

ATP-binding cassette (ABC) transporter genes are involved in the regulation of the amount of dietary cholesterol retained in the body. ABCG8, expressed at high levels in the liver and intestine, normally cooperates with ABCG5 to limit intestinal absorption and promote biliary excretion of sterols. The mutated form of this transporter can lead to sterol accumulation and atherosclerosis or sitosterolemia, a rare autosomal recessive disorder, characterized by hyperabsorption of sterols and the inability to excrete sterols into bile.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ATP-binding cassette sub-family G member 8; ATP-binding cassette, sub-family G (WHITE), member 8; ATP-binding cassette, subfamily G, member 8; MGC142217; sterolin 2; Sterolin-2; Sterolin2

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基因别名: 1300003C16Rik; ABCG8; AI114946; GBD4; sterolin-2; STSL

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UniProt ID: (Human) Q9H221, (Mouse) Q9DBM0

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Entrez Gene ID: (Human) 64241, (Mouse) 67470

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