Search Thermo Fisher Scientific
Immunogen sequence: PSSTAPDAAA GGAQTLADGF TSPTPPVVSS TPPTGHPVQF YSMNRPASRH T
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 51%.
ABI2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. ABI2 is a part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. It regulates ABL1/c-Abl-mediated phosphorylation of MENA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Abelson interactor 2; Abi-2; abl binding protein 3; Abl interactor 2; Abl-binding protein 3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AblBP3; arg protein tyrosine kinase-binding protein; Arg-binding protein 1; ArgBP1
基因别名: ABI-2; ABI2; ABI2B; AblBP3; AIP-1; argBP1; ARGBPIA; argBPIB; SSH3BP2
UniProt ID: (Human) Q9NYB9
Entrez Gene ID: (Human) 10152