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ACADL Antibody (PA5-116549) in IHC (P)
Immunohistochemistry analysis of ACADL in paraffin-embedded human lung cancer. Samples were incubated with ACADL Polyclonal antibody (Product # PA5-116549) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-116549
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 31-210 of human ACADL (NP_0015991)
偶联物
形式
Liquid
浓度
1.2 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901180
产品详细信息
Positive Samples: SH-SY5Y, Mouse liver, Mouse kidney, Mouse heart, Rat spinal cord
Immunogen sequence: GGEERLETPS AKKLTDIGIR RIFSPEHDIF RKSVRKFFQE EVIPHHSEWE KAGEVSREVW EKAGKQGLLG VNIAEHLGGI GGDLYSAAIV WEEQAYSNCS GPGFSIHSGI VMSYITNHGS EEQIKHFIPQ MTAGKCIGAI AMTEPGAGSD LQGIKTNAKK DGSDWILNGS KVFISNGSLS
靶标信息
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD; LCAD long chain acyl-CoA dehydrogenase; long-chain acyl-CoA dehydrogenase; Long-chain specific acyl-CoA dehydrogenase, mitochondrial
基因别名: AA960361; ACAD4; ACADL; ACOADA; AU018452; C79855; LCAD
UniProt ID: (Human) P28330, (Mouse) P51174, (Rat) P15650
Entrez Gene ID: (Human) 33, (Mouse) 11363, (Rat) 25287
fatty-acyl-CoA binding
acyl-CoA dehydrogenase activity
long-chain-acyl-CoA dehydrogenase activity
electron carrier activity
palmitoyl-CoA oxidase activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
temperature homeostasis
fatty acid beta-oxidation
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
cellular lipid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
protein homotetramerization
lipid homeostasis
oxidation-reduction process
regulation of cholesterol metabolic process
lipid metabolic process
fatty acid metabolic process
metabolic process
