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ACAT1 Antibody (PA5-34676) in ICC/IF
ACAT1 Polyclonal Antibody detects ACAT1 protein at mitochondria by immunofluorescent analysis. Sample: A431 cells were fixed in 2% paraformaldehyde/culture medium at 37°C for 30 min. Green: ACAT1 protein stained by ACAT1 Polyclonal Antibody (Product # PA5-34676) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-34676
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 151 of ACAT1 (Uniprot ID#P24752)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2552028
产品详细信息
Recommended positive controls: 293T, A431, Molt-4, mouse brain, F31, F90.
Predicted reactivity: Mouse (84%), Rat (83%), Zebrafish (80%), Rhesus Monkey (98%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ACAT-1 is a ~50 kDa protein that catalyzes the formation of intracellular cholesterol esters in various tissues, such as adult human liver, adrenal glands, macrophages, and kidneys.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acetoacetyl Coenzyme A thiolase; Acetoacetyl-CoA thiolase; Acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; mitochondrial acetoacetyl-CoA thiolase; T2; testicular tissue protein Li 198
基因别名: 6330585C21Rik; ACAT; ACAT1; MAT; T2; THIL
UniProt ID: (Human) P24752, (Mouse) Q8QZT1
Entrez Gene ID: (Human) 38, (Mouse) 110446
acetyl-CoA C-acetyltransferase activity
enzyme binding
protein homodimerization activity
metal ion binding
coenzyme binding
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
acyltransferase
liver development
brain development
branched-chain amino acid catabolic process
response to hormone
response to organic cyclic compound
response to starvation
ketone body biosynthetic process
ketone body catabolic process
protein homooligomerization
adipose tissue development
metanephric proximal convoluted tubule development
metabolic process
