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ACAT2 Antibody (MA5-42668) in WB
Western blot analysis of ACAT2 in extracts of various cell lines. Samples were incubated with ACAT2 Monoclonal antibody (Product # MA5-42668) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
MA5-42668
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6Z5L1
抗原
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human ACAT2 (Q9BWD1).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911809
产品详细信息
Positive test controls include: HeLa, SW620, HepG2, Mouse liver, Mouse brain, Mouse kidney, Rat brain, Rat kidney. The target is usually found in the following locations: Cytoplasm.
Immunogen sequence: GLTDAFHNCH MGITAENVAK KWQVSREDQD KVAVLSQNRT ENAQKAGHFD KEIVPVLVST RKGLIEVKTD EFPRHGSNIE AMSKLKPYFL TDGTGTVTPA N
靶标信息
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetoacetyl Coenzyme A thiolase; Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2; acetyl-Coenzyme A acetyltransferase 3; AE1; BND3; CD233; Cytosolic acetoacetyl-CoA thiolase; DI; EMPB3; EPB3; FR; RTA1A; SW; t-complex protein 1, related sequence 1; WD; WD1; WR
基因别名: Ab2-076; ACAT2; Acat3; ACTL; AW742799; Tcp-1x; Tcp1-rs1
UniProt ID: (Human) Q9BWD1, (Rat) Q5XI22, (Mouse) Q8CAY6
Entrez Gene ID: (Human) 39, (Rat) 308100, (Mouse) 110460
