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产品信息
PA5-101415
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ACER2(Accession Q5QJU3), corresponding to amino acid residues Y209-P259.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2850851
产品详细信息
Antibody detects endogenous levels of total ASAH3L.
靶标信息
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acylsphingosine deacylase 3-like; alkaline CDase 2; Alkaline ceramidase 2; AlkCDase 2; cancer related gene-liver 1 (CRG-L1); Cancer-related gene liver 1 protein; ceramide hydrolase; CRG-L1; haCER2; N-acylsphingosine amidohydrolase 3-like
基因别名: 2410116I05Rik; ACER2; ALKCDase2; ASAH3L; CRG-L1; maCER2; PP11646
UniProt ID: (Human) Q5QJU3, (Mouse) Q8VD53
Entrez Gene ID: (Human) 340485, (Mouse) 230379
negative regulation of cell-matrix adhesion
ceramide metabolic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of cell death
sphingolipid biosynthetic process
response to retinoic acid
negative regulation of cell adhesion mediated by integrin
cellular response to drug
sphingosine biosynthetic process
negative regulation of protein glycosylation in Golgi
lipid metabolic process
