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产品信息
PA5-114249
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the middle region of Human ACER2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2884763
产品详细信息
Immunogen sequence: DELAVLWVLM CALAMWFPRR YLPKIFRNDR GRFKVVVSVL SAVTTCLAFV
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
靶标信息
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acylsphingosine deacylase 3-like; alkaline CDase 2; Alkaline ceramidase 2; AlkCDase 2; ceramide hydrolase; haCER2; N-acylsphingosine amidohydrolase 3-like
基因别名: ACER2; ALKCDase2; ASAH3L; PP11646
UniProt ID: (Human) Q5QJU3
Entrez Gene ID: (Human) 340485
negative regulation of cell-matrix adhesion
ceramide metabolic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of cell death
sphingolipid biosynthetic process
response to retinoic acid
negative regulation of cell adhesion mediated by integrin
cellular response to drug
sphingosine biosynthetic process
negative regulation of protein glycosylation in Golgi
