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产品信息
PA5-75832
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues in Human ACER2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719560
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acylsphingosine deacylase 3-like; alkaline CDase 2; Alkaline ceramidase 2; AlkCDase 2; ceramide hydrolase; haCER2; N-acylsphingosine amidohydrolase 3-like
基因别名: ACER2; ALKCDase2; ASAH3L; PP11646
UniProt ID: (Human) Q5QJU3
Entrez Gene ID: (Human) 340485, (Rat) 313339
negative regulation of cell-matrix adhesion
ceramide metabolic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of cell death
sphingolipid biosynthetic process
response to retinoic acid
negative regulation of cell adhesion mediated by integrin
cellular response to drug
sphingosine biosynthetic process
negative regulation of protein glycosylation in Golgi
biological_process
