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产品信息
PA5-84443
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2791594
产品详细信息
Immunogen sequence: MSNKLLSPHP HSVVLRSEFK MASSPAVLRA SRLYQWSLKS SAQFLGSPQL RQVGQIIRVP AR
靶标信息
Acyl-CoA thioesterases (ACOTs) are a group of enzymes that catalyze the hydrolysis of acyl-CoA to form coenzyme A (CoA) and a free fatty acid. Through their catalytic activity, ACOTs are able to regulate the level of fatty acids and acyl-CoAs within the cell. ACOT1 (acyl-CoA thioesterase 1, also known as CTE1) and ACOT2 (acyl-CoA thioesterase 2, also known as PTE2) are members of the ACOT family and exhibit different cellular localization, with ACOT1 existing as a monomer in the cytoplasm and ACOT2 localized primarily to mitochondria. Characteristic of most ACOT proteins, ACOT1 and ACOT2 catalyze the conversion of Palmitoyl-CoA and water to free CoA and palmitate, a reaction that is important for the regulation of intercellular fatty acid levels. ACOT2 is expressed as multiple alternatively spliced isoforms and, like ACOT1, is encoded by a gene which maps to human chromosome 14.
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生物信息学
蛋白别名: Acyl-CoA thioesterase 2; Acyl-coenzyme A thioester hydrolase 2a; Acyl-coenzyme A thioesterase 2, mitochondrial; CTE Ia; CTE-Ia; Long-chain acyl-CoA thioesterase 2; mitochondrial acyl-CoA thioesterase 1; peroxisomal long-chain acyl-coA thioesterase 2; ZAP128
基因别名: ACOT2; CTE-IA; CTE1A; MTE1; PTE2; PTE2A; ZAP128
UniProt ID: (Human) P49753
Entrez Gene ID: (Human) 10965
