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ACOT8 Antibody (PA5-26152) in IHC (P)
Immunohistochemistry analysis of ACOT8 in formalin-fixed and paraffin-embedded human prostate carcinoma. Samples were incubated with ACOT8 polyclonal antibody (Product # PA5-26152) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
产品信息
PA5-26152
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 290-319 amino acids from the C-terminal region of human ACOT8
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2543652
靶标信息
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acyl-CoA thioesterase 8; Acyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; Choloyl-coenzyme A thioesterase; hACTE-III; HIV-Nef associated acyl-CoA thioesterase; HIV-Nef-associated acyl-CoA thioesterase; long-chain fatty-acyl-CoA hydrolase; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; Peroxisomal acyl-CoA thioesterase 2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; Peroxisomal long-chain acyl-CoA thioesterase 1; PTE-1; PTE-2; Thioesterase II; thioesterase III
基因别名: ACOT8; ACTEIII; hACTE-III; HNAACTE; hTE; NAP1; PTE-1; PTE-2; PTE1; PTE2
UniProt ID: (Human) O14734, (Mouse) P58137
Entrez Gene ID: (Human) 10005, (Mouse) 170789
acetyl-CoA hydrolase activity
receptor binding
protein binding
CoA hydrolase activity
palmitoyl-CoA hydrolase activity
choloyl-CoA hydrolase activity
acyl-CoA hydrolase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
hydrolase activity
acyl-CoA metabolic process
bile acid biosynthetic process
viral process
peroxisome fission
fatty acid beta-oxidation using acyl-CoA oxidase
long-chain fatty-acyl-CoA biosynthetic process
alpha-linolenic acid metabolic process
dicarboxylic acid catabolic process
negative regulation of CD4 biosynthetic process
peroxisome organization
