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ACOX2 Antibody (PA5-114814) in ICC/IF
Immunocytochemistry analysis of ACOX2 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114814). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-114814
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ACOX2(Accession Q99424), corresponding to amino acid residues L309-F359.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899450
产品详细信息
Antibody detects endogenous levels of total ACOX2.
靶标信息
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; acyl-CoA oxidase 2, branched chain; acyl-Coenzyme A oxidase 2, branched chain; branched chain acyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 2; peroxisomal branched chain acyl-CoA oxidase; THCA-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase
基因别名: ACOX2; BCOX; BRCACOX; BRCOX; THCCox
UniProt ID: (Human) Q99424, (Mouse) Q9QXD1
Entrez Gene ID: (Human) 8309, (Rat) 252898, (Mouse) 93732
fatty-acyl-CoA binding
acyl-CoA dehydrogenase activity
acyl-CoA oxidase activity
receptor binding
fatty acid binding
electron carrier activity
pristanoyl-CoA oxidase activity
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
oxidoreductase
