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Recommended positive controls: A549, mouse liver.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Acyl-Coenzyme A oxidase 3 also know as pristanoyl-CoA oxidase (ACOX3) is involved in the desaturation of 2-methyl branched fatty acids in peroxisomes. Unlike the rat homolog, the human gene is expressed in very low amounts in liver such that its mRNA was undetectable by routine Northern-blot analysis or its product by immunoblotting or by enzyme activity measurements. However the human cDNA encoding a 700 amino acid protein with a peroxisomal targeting C-terminal tripeptide S-K-L was isolated and is thought to be expressed under special conditions such as specific developmental stages or in a tissue specific manner in tissues that have not yet been examined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acyl-Coenzyme A oxidase 3, pristanoyl; Branched-chain acyl-CoA oxidase; BRCACox; Peroxisomal acyl-coenzyme A oxidase 3; Pristanoyl-CoA oxidase
Gene Aliases: ACOX3; BI685180; BRCOX; EST-s59; PCOX; PRCOX
UniProt ID: (Human) O15254, (Mouse) Q9EPL9
Entrez Gene ID: (Human) 8310, (Mouse) 80911
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