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Product Details
PA5-53567
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ACPL2. Recombinant protein control fragment (Product #RP-90339).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637613
Product Specific Information
Immunogen sequence: STPKNGMSSK SRKRIMPDPV TEPPVTDPVY EALLYCNIPS VAERSMEGHA PHHFKLVSVH VFIRHGDRYP LYVIPKTKRP EIDCTLVANR KPYHPKLEAF ISHMSKGSGA SFESPLNSLP LYPNHP
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.
Target Information
Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-phosphoxylose phosphatase 1; acid phosphatase-like 2; Acid phosphatase-like protein 2; epididymis luminal protein 124; PXYLP1 (HGNC:26303); Xylosyl phosphatase
Gene Aliases: ACPL2; HEL124; PXYLP1; UNQ370/PRO706; XYLP
UniProt ID: (Human) Q8TE99
Entrez Gene ID: (Human) 92370
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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