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ACSL3 Antibody (PA5-88208) in IHC (P)
Immunohistochemistry analysis of ACSL3 in paraffin-embedded human mammary cancer. Samples were incubated with ACSL3 Polyclonal antibody (Product # PA5-88208) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-88208
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 621-720 of human ACSL3 (NP_0044482)
偶联物
形式
Liquid
浓度
1.53 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804743
产品详细信息
Positive Samples: HeLa, Mouse kidney; Cellular Location: Endoplasmic reticulum membrane, Microsome membrane, Mitochondrion outer membrane, Peroxisome membrane, Single-pass type III membrane protein
Immunogen sequence: CEMENEVLKV LSEAAISASL E
靶标信息
An initial reaction in fatty acid metabolism in eukaryotic cells is activation of fatty acids catalyzed by acyl-CoA synthetase. FACL3 (fatty acid CoA ligase, long-chain 3) is identified as member of the acyl-CoA synthetase (ACS) family by PCR of rat brain cDNAs using primers based on the conserved region of the ACS protein. The 720-amino acid rat protein preferentially utilizes myristate, laurate, arachidonate, and eicosapentaenoate, and is expressed primarily in brain. The predicted 720-amino acid FACL3 human protein is 92% identical to that of rat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Arachidonate--CoA ligase; Arachidonate--CoA ligase Acsl3; Brain acyl-CoA synthetase II; Fatty acid CoA ligase Acsl3; fatty acid Coenzyme A ligase, long chain 3; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; Medium-chain acyl-CoA ligase Acsl3
基因别名: 2610510B12Rik; ACS3; ACSL3; C85929; FACL3; LACS3; PRO2194
UniProt ID: (Human) O95573, (Rat) Q63151, (Mouse) Q9CZW4
Entrez Gene ID: (Human) 2181, (Rat) 114024, (Mouse) 74205
long-chain fatty acid metabolic process
fatty acid biosynthetic process
brain development
response to nutrient
response to organic cyclic compound
very-low-density lipoprotein particle assembly
long-chain fatty-acyl-CoA biosynthetic process
positive regulation of Golgi to plasma membrane protein transport
long-chain fatty acid import
positive regulation of secretion
positive regulation of phosphatidylcholine biosynthetic process
lipid metabolic process
fatty acid metabolic process
metabolic process
