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Immunogen sequence: PGETTQITYH QLLVQVCQFS NVLRKQGIQK GDRVAIYMPM IPELVVAMLA CARIGALHSI VFAGFSSESL CERILDSSCS LLITTDAFYR GEKLVNLKEL ADEALQKCQE KGFPVRCCIV VKHLGRAELG MGDSTSQSPP IKRSCPDVQ
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AceCS1; acetate thiokinase; Acetate--CoA ligase; acetate-CoA ligase; Acetyl-CoA synthetase; Acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 2 (ADP forming); Acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acyl-activating enzyme; Acyl-CoA synthetase short-chain family member 2; cytoplasmic acetyl-coenzyme A synthetase; Propionate--CoA ligase
基因别名: ACAS2; ACECS; ACS; ACSA; ACSS2; dJ1161H23.1
UniProt ID: (Human) Q9NR19
Entrez Gene ID: (Human) 55902