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ADAM9 Antibody (PA5-47968) in WB
Western blot analysis of ADAM9 in WI‚38 human lung fibroblast cell line and U‚87 MG human glioblastoma/astrocytoma cell line. Samples were incubated in ADAM9 polyclonal antibody (Product # PA5-47968) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. Specific bands were detected for ADAM9 at approximately 110 and 80 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47968
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human ADAM9 Ala206-Asp697
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2607933
产品详细信息
In sandwich ELISAs, approximately 20% cross-reactivity with recombinant mouse (rm) rmADAM9 is observed and less than 0.05% cross-reactivity with recombinant human (rh) rhADAM8, rhADAM10, rhTACE, rhTIMP-1, rhTIMP-2, rhTIMP-3, rhTIMP-4, rhBACE-1 and rmADAM10 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: a disintegrin and metalloproteinase; ADAM; ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); ADAMs; Cellular disintegrin-related protein; cone rod dystrophy 9; Disintegrin and metalloproteinase domain-containing protein 9; MDC 9; Meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485
基因别名: ADAM9; CORD9; KIAA0021; MCMP; MDC9; MLTNG
UniProt ID: (Human) Q13443
Entrez Gene ID: (Human) 8754
activation of MAPKK activity
membrane protein ectodomain proteolysis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
response to manganese ion
cell migration
keratinocyte differentiation
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
cell-cell adhesion mediated by integrin
positive regulation of macrophage fusion
response to tumor necrosis factor
monocyte activation
response to hydrogen peroxide
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
PMA-inducible membrane protein ectodomain proteolysis
response to glucocorticoid
positive regulation of keratinocyte migration
response to calcium ion
cellular response to lipopolysaccharide
