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Immunogen sequence: LHGVIATEDE EYFIEPLKNT TEDSKHFSYE NGHPHVIYKK SALQQRHLYD HSHCGVSDFT RSGKPWWLND TSTVSYSLPI NNTHIHHRQK RSVSIERFVE
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 6; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 6; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 6; ADAM-TS 6; ADAMs; metalloendopeptidases
基因别名: ADAM-TS 6; ADAM-TS6; ADAMTS-6; ADAMTS6
UniProt ID: (Human) Q9UKP5
Entrez Gene ID: (Human) 11174