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Immunogen sequence: MVQAWYMDDA PGDPRQPHRP DPGRPVGLEQ LRRLGVLYWK LDADKYENDP ELEKIRRERN YSWMDIITIC KDKLPNYEEK IKMFYEEHLH LDDEIRYILD GSGYFDVRDK EDQWIRIFME KGDMVTLPAG IYHRFTVDEK NYTKAMRLFV GEPVWTAYNR PADHFEARGQ YVKFLAQTA; Positive Samples: U-87MG, A-549, SGC7901, HT-29, 293T, HepG2; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein
This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. A pseudogene that is located on chromosome 20 has been defined for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}; aci-reductone dioxygenase; aci-reductone dioxygenase (ARD)-like protein 1; Acireductone dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}; Acireductone dioxygenase (Ni(2+)-requiring); Androgen-responsive ARD-like protein 1; androgen-responsive gene encoding an ARD-like protein; ARD; ARD {ECO:0000255|HAMAP-Rule:MF_03154}; ARD'; fe-ARD; fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}; membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}; MT1-MMP cytoplasmic tail-binding protein-1; MTCBP-1; MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}; Sip-L; submergence induced protein 2; Submergence-induced protein-like factor
基因别名: ADI1; AL024210; Alp1; APL1; ARD; Fe-ARD; HMFT1638; MTCBP-1; MTCBP1; mtnD; Ni-ARD; SIPL
UniProt ID: (Human) Q9BV57, (Rat) Q562C9, (Mouse) Q99JT9
Entrez Gene ID: (Human) 55256, (Rat) 298934, (Mouse) 104923