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产品信息
PA5-45051
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human ADORA3
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2608948
产品详细信息
Peptide sequence: RSCKAPKVVR KADRSRTSIL IICILITGLG IISVISHLTK RRRSQRNRRV
Sequence homology: Cow: 75%; Horse: 93%; Human: 100%; Pig: 85%; Rabbit: 77%
靶标信息
Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response and the inhibition of protein synthesis The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthesis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNF alpha and blocks the endotoxin CD14 receptor signal transduction pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AD026; Adenosine A3-R; Adenosine receptor A3; BA552M11.5; RP11-552M11.7
基因别名: A3AR; ADORA3
UniProt ID: (Human) P0DMS8
Entrez Gene ID: (Human) 140
