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产品信息
PA5-52080
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Dog
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2637746
产品详细信息
Immunogen sequence: KTLLAKATAG EANVPFITVS GSEFLEMFVG VGPARVRDLF ALARKNAPCI LFIDEIDAVG RKRGRGNFGG QSEQENTLNQ LLVEMDGFNT TTNVVILAGT NRPDILDPAL LRPGRFDRQI FIGPPDIKGR ASIFKVHLRP LK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
靶标信息
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AFG3 ATPase family gene 3-like 2; AFG3 ATPase family member 3-like 2; AFG3 like AAA ATPase 2; AFG3-like AAA ATPase 2; AFG3-like protein 2; ATPase family gene 3, yeast; FLJ25993; Mitochondrial inner membrane m-AAA protease component AFG3L2; Paraplegin-like protein
基因别名: AFG3L2; SCA28; SPAX5
UniProt ID: (Human) Q9Y4W6
Entrez Gene ID: (Human) 10939
protein complex assembly
axonogenesis
neuromuscular junction development
mitochondrial fusion
nerve development
mitochondrial protein processing
regulation of multicellular organism growth
cristae formation
myelination
protein import into mitochondrial intermembrane space
muscle fiber development
righting reflex
