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AFG3L2 Antibody (PA5-85156) in IHC (P)
AFG3L2 Polyclonal Antibody detects AFG3L2 protein at cytoplasm in rat pancreas by immunohistochemical analysis. Sample: Paraffin-embedded rat pancreas. AFG3L2 Polyclonal Antibody (Product # PA5-85156) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-85156
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human AFG3L2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792303
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Bovine (86%).
Positive Control: SK-N-SH membrane fraction extract.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AFG3 ATPase family gene 3-like 2; AFG3 ATPase family member 3-like 2; AFG3 like AAA ATPase 2; AFG3-like AAA ATPase 2; AFG3-like protein 2; ATPase family gene 3, yeast; FLJ25993; Mitochondrial inner membrane m-AAA protease component AFG3L2; Paraplegin-like protein
Gene Aliases: AFG3L2; SCA28; SPAX5
UniProt ID: (Human) Q9Y4W6
Entrez Gene ID: (Human) 10939, (Rat) 307350
protein complex assembly
axonogenesis
neuromuscular junction development
mitochondrial fusion
nerve development
mitochondrial protein processing
regulation of multicellular organism growth
cristae formation
myelination
protein import into mitochondrial intermembrane space
muscle fiber development
righting reflex
proteolysis
mitochondrion organization
obsolete death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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