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产品信息
PA5-101548
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human AGBL4(Accession Q5VU57), corresponding to amino acid residues Y437-K487.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2850982
产品详细信息
Antibody detects endogenous levels of total AGBL4.
靶标信息
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP/GTP binding protein-like 4; ATP/GTP-binding protein-like 4; Cytosolic carboxypeptidase 6; Protein deglutamylase CCP6
基因别名: AGBL4; CCP6
UniProt ID: (Human) Q5VU57
Entrez Gene ID: (Human) 84871
