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产品信息
PA5-62795
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2637760
产品详细信息
Immunogen sequence: IVKGETVPLD VLQIKGEKEQ PVFAMTGLRW GSFRDAGVKV SKYWYLGPLK IKAAHFFSTL KEWPQTHQAS ISYTGPTERP PNEPEETPVQ RPSLYRRILR RLASYWAQ
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 90%.
靶标信息
Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acylglycerol kinase, mitochondrial; FLJ10842; hAGK; HsMuLK; multi-substrate lipid kinase; Multiple substrate lipid kinase
基因别名: AGK; CATC5; CTRCT38; MTDPS10; MULK
UniProt ID: (Human) Q53H12
Entrez Gene ID: (Human) 55750
