Invitrogen

AGPAT4 Polyclonal Antibody

AGPAT4 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 8

AGPAT4 Antibody (PA5-62768) in ICC/IF

Immunofluorecent analysis of AGPAT4 in human cell line U-251 MG using AGPAT4 Polyclonal Antibody (Product # PA5-62768). Staining shows positivity in vesicles.

AGPAT4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

AGPAT4 Antibody in Immunohistochemistry (IHC)

Product Image Gallery

产品信息

PA5-62768

应用

建议稀释比

已发表文章

免疫印迹 (WB)

查看1篇已发表文章 1篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human AGPAT4. Recombinant protein control fragment (Product #RP-101093).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2637765

产品详细信息

Immunogen sequence: VTEIDKGSAY GNSDSKQKLN D

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 76%.

靶标信息

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. [provided by RefSeq, Jul 2008].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.

Signal transduction and targeted therapy

Zhang D,Shi R,Xiang W,Kang X,Tang B,Li C,Gao L,Zhang X,Zhang L,Dai R,Miao H

PA5-62768 was used in Western Blot, Immunohistochemistry to show that the Agpat4/LPA axis in CRC cells regulated p38/p65 signaling-dependent macrophage polarization, T-cell activation, and CRC progression.

Fri Mar 27 00:00:00 UTC 2020

The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.

Signal transduction and targeted therapy

Zhang D,Shi R,Xiang W,Kang X,Tang B,Li C,Gao L,Zhang X,Zhang L,Dai R,Miao H

Fri Mar 27 00:00:00 UTC 2020

The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.

Signal transduction and targeted therapy

Zhang D,Shi R,Xiang W,Kang X,Tang B,Li C,Gao L,Zhang X,Zhang L,Dai R,Miao H

Fri Mar 27 00:00:00 UTC 2020

The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages.

Signal transduction and targeted therapy

Zhang D,Shi R,Xiang W,Kang X,Tang B,Li C,Gao L,Zhang X,Zhang L,Dai R,Miao H

Fri Mar 27 00:00:00 UTC 2020

生物信息学

蛋白别名: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); 1-AGP acyltransferase 4; 1-AGPAT 4; LPAAT-delta; Lysophosphatidic acid acyltransferase delta; lysophosphatidic acid acyltransferase-delta (LPAAT-delta)

查看更多收起

基因别名: 1-AGPAT4; AGPAT4; dJ473J16.2; LPAAT-delta; UNQ499/PRO1016

查看更多收起

UniProt ID: (Human) Q9NRZ5

查看更多收起

Entrez Gene ID: (Human) 56895

查看更多收起

功能

1-acylglycerol-3-phosphate O-acyltransferase activity protein binding acyltransferase

参与通路

phosphatidic acid biosynthetic process phospholipid biosynthetic process CDP-diacylglycerol biosynthetic process triglyceride biosynthetic process