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AGXT Antibody (PA5-109370) in WB
Western blot analysis of AGXT in extracts of rat skeletal muscle. Samples were incubated with AGXT Polyclonal antibody (Product # PA5-109370) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.
产品信息
PA5-109370
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human AGXT (NP_000021.1).
偶联物
形式
Liquid
浓度
0.9 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2854781
产品详细信息
Immunogen sequence: DSVASLGGTP LYMDRQGIDI LYSGSQKALN APPGTSLISF SDKAKKKMYS RKTKPFSFYL DIKWLANFWG CDDQPRMYHH TIPVISLYSL RESLALIAEQ GLENSWRQHR EAAAYLHGRL QALGLQLFVK DPALRLPTVT TVAVPAGYDW RDIVSYVIDH FDIEIMGGLG PSTGKVLRIG LLGCNATREN VDRVTEALRA ALQHCPKKKL
靶标信息
This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AGT; Alanine--glyoxylate aminotransferase; alanine-glyoxylate aminotransferase 1; angiotensin receptor 2; Serine--pyruvate aminotransferase, mitochondrial; serine--pyruvate aminotransferase, peroxisomal; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase SPT; serine:pyruvate/alanine:glyoxylate aminotransferase; SPT
基因别名: AGT; Agt1; Agxt; Agxt1; Spat; SPT
UniProt ID: (Rat) P09139, (Mouse) O35423
Entrez Gene ID: (Rat) 24792, (Mouse) 11611
glyoxylate catabolic process
glycine biosynthetic process, by transamination of glyoxylate
L-cysteine catabolic process
L-alanine catabolic process
pyruvate biosynthetic process
glyoxylate metabolic process
oxalic acid secretion
response to glucocorticoid
response to cAMP
Notch signaling pathway
metabolic process
