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产品信息
199-MSM2-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rAIF1, 1909
抗原
Purified recombinant human AIF1 protein (around aa 1-146)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
AIF1 is induced by cytokines and interferon. It is thought to be involved in the negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIF-1; Allograft inflammatory factor 1; DADB-70P7.8; DASS-82G15.2; Em:AF129756.17; Iba; interferon gamma responsive transcript; Ionized calcium-binding adapter molecule 1; Protein G1
基因别名: AIF-1; AIF1; G1; IBA1; IRT-1; IRT1
UniProt ID: (Human) P55008
Entrez Gene ID: (Human) 199
microglial cell activation
positive regulation of protein phosphorylation
phagocytosis, engulfment
inflammatory response
negative regulation of gene expression
positive regulation of muscle hyperplasia
Rac protein signal transduction
actin filament polymerization
cellular response to extracellular stimulus
cellular response to hormone stimulus
positive regulation of T cell proliferation
negative regulation of apoptotic process
positive regulation of nitric oxide biosynthetic process
positive regulation of smooth muscle cell proliferation
negative regulation of smooth muscle cell proliferation
response to axon injury
actin filament bundle assembly
response to glucocorticoid
response to electrical stimulus
cellular response to morphine
cellular response to interferon-gamma
cellular response to hydroperoxide
negative regulation of smooth muscle cell chemotaxis
positive regulation of smooth muscle cell chemotaxis
positive regulation of monocyte chemotaxis
ruffle assembly
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of T cell migration
