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Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The protein anchors PKA in ciliary axonemes and, in this way, may play a role in regulating ciliary beat frequency. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A kinase (PRKA) anchor protein 14; A-kinase anchor protein 14; A-kinase anchor protein 28 kDa; A-kinase anchoring protein 28; AKAP 28; AKAP-14; PRKA14; Protein kinase A-anchoring protein 14; TAKAP-1.2; Testis-specific A-kinase-anchoring protein TAKAP-80; Testis-specific A-kinase-anchoring-protein
基因别名: AKAP14; AKAP28; PRKA14; Takap80
UniProt ID: (Human) Q86UN6, (Rat) O35817
Entrez Gene ID: (Human) 158798, (Rat) 60332, (Mouse) 434756