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AKAP7 Antibody (PA5-88238) in WB
Western blot analysis of AKAP7 in extracts of various cell lines. Samples were incubated with AKAP7 Polyclonal antibody (Product # PA5-88238) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88238
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-81 of human AKAP7 (NP_0048331)
偶联物
形式
Liquid
浓度
3.28 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804765
产品详细信息
Immunogen sequence: MGQLCCFPFS RDEGKISEKN GGEPDDAELV RLSKRLVENA VLKAVQQYLE ETQNKNKPGE GSSVKTEAAD QNGNDNENNR K; Positive Samples: Mouse brain, Rat brain; Cellular Location: Apical cell membrane, Lateral cell membrane, Lipid-anchor, Lipid-anchor
靶标信息
This gene encodes a member of the A-kinase anchoring protein family, a group of functionally related proteins that bind to a regulatory subunit of cAMP-dependent protein kinase A and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. Additional variants exist, but their full-length natures have not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A kinase (PRKA) anchor protein 7; A-kinase anchor protein 18; A-kinase anchor protein 18 kDa; A-kinase anchor protein 18 {ECO:0000250|UniProtKB:F8VQ58}; A-kinase anchor protein 7; A-kinase anchor protein 7 isoform alpha; A-kinase anchor protein 7 isoform gamma; A-kinase anchor protein 7 isoforms alpha and beta; A-kinase anchor protein 7 isoforms delta and gamma; A-kinase anchor protein 9 kDa; A-kinase anchoring protein 18 ,isoform delta; AKAP 18; AKAP 9; AKAP-18; AKAP-18 {ECO:0000250|UniProtKB:F8VQ58}; AKAP-7 isoform alpha; AKAP-7 isoform gamma; AKAP-7 isoforms alpha and beta; AKAP-7 isoforms delta and gamma; akap7; akap7 {ECO:0000312|RGD:1303071}; PRKA7 isoform alpha; PRKA7 isoform gamma; PRKA7 isoforms alpha/beta; PRKA7 isoforms delta and gamma; protein kinase A anchoring protein 7; Protein kinase A-anchoring protein 7 isoform alpha; Protein kinase A-anchoring protein 7 isoform gamma; Protein kinase A-anchoring protein 7 isoforms alpha/beta; Protein kinase A-anchoring protein 7 isoforms delta and gamma
基因别名: 6430401D08; AI662165; AKAP-18; AKAP15; AKAP18; AKAP18d; AKAP7; BB170514
UniProt ID: (Human) O43687, (Mouse) O55074, (Rat) Q6JP77
Entrez Gene ID: (Human) 9465, (Mouse) 432442, (Rat) 361458
biological_process
transmembrane receptor protein serine/threonine kinase signaling pathway
protein localization
regulation of protein kinase A signaling
regulation of membrane repolarization
cellular response to cAMP
positive regulation of potassium ion transmembrane transport
positive regulation of delayed rectifier potassium channel activity
