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AKR1B1 Antibody (MA5-55881) in IHC (P)
Immunohistochemistry analysis of AKR1B1 in paraffin-embedded adrenal gland tissue. Sample was incubated with AKR1B1 monoclonal antibody (Product # MA5-55881) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temper... View More
Product Details
MA5-55881
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
K92029_13G7
Immunogen
Recombinant human AKR1B1 (immunogen range is 11-290).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
Sequence of this protein is as follows: AKMPILGLGT WKSPPGQVTE AVKVAIDVGY RHIDCAHVYQ NENEVGVAIQ EKLREQVVKR EELFIVSKLW CTYHEKGLVK GACQKTLSDL KLDYLDLYLI HWPTGFKPGK EFFPLDESGN VVPSDTNILD TWAAMEELVD EGLVKAIGIS NFNHLQVEMI LNKPGLKYKP AVNQIECHPY LTQEKLIQYC QSKGIVVTAY SPLGSPDRPW AKPEDPSLLE DPRIKAIAAK HNKTTAQVLI RFPMQRNLVV IPKSVTPERI AENFKVFDFE LSSQDMTTLL
Target Information
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aldehyde reductase; aldehyde reductase 1; aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase)
Gene Aliases: ADR; AKR1B1; ALDR1; ALR2; AR
UniProt ID: (Human) P15121
Entrez Gene ID: (Human) 231
tissue homeostasis
carbohydrate metabolic process
sorbitol biosynthetic process
C21-steroid hormone biosynthetic process
response to stress
response to water deprivation
naphthalene metabolic process
stress-activated protein kinase signaling cascade
norepinephrine metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
fructose biosynthetic process
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
oxidation-reduction process
maternal process involved in female pregnancy
cellular response to hydrogen peroxide
inner medullary collecting duct development
response to thyroid hormone
cellular response to methylglyoxal
cellular response to peptide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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