Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
MA5-15593
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Non-human primate,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
1B6
抗原
Purified recombinant fragment of human AKT2 expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_10974323
产品详细信息
MA5-15593 targets AKT2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human, Non-human primate, and Rat samples.
The MA5-15593 immunogen is purified recombinant fragment of human AKT2 expressed in E. Coli.
MA5-15593 detects AKT2 which has a predicted molecular weight of approximately 60kDa.
靶标信息
AKT2 is a phosphoinositide-dependent serine/threonine protein kinase that is enriched in insulin responsive tissues and has been implicated in the metabolic actions of the hormone. Akt is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: AKT2 kinase; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 2; PKB beta; Protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; thymoma viral proto-oncogene 2; v-akt murine thymoma viral oncogene homolog 2
基因别名: AKT2; HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
UniProt ID: (Human) P31751, (Rat) P47197
Entrez Gene ID: (Human) 208, (Rat) 25233
positive regulation of protein phosphorylation
glycogen biosynthetic process
glucose metabolic process
regulation of translation
protein phosphorylation
response to osmotic stress
multicellular organism development
insulin receptor signaling pathway
carbohydrate transport
positive regulation of signal transduction
positive regulation of gene expression
negative regulation of plasma membrane long-chain fatty acid transport
positive regulation of sodium ion transport
positive regulation of glucose metabolic process
response to muscle activity
positive regulation of cell migration
positive regulation of vesicle fusion
response to nutrient levels
positive regulation of fatty acid beta-oxidation
peripheral nervous system myelin maintenance
response to insulin
cellular response to insulin stimulus
cellular response to hormone stimulus
negative regulation of RNA splicing
positive regulation of peptidyl-serine phosphorylation
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
positive regulation of nitric oxide biosynthetic process
positive regulation of glycogen biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
positive regulation of positive chemotaxis
intracellular protein transmembrane transport
cellular response to organic cyclic compound
protein localization to plasma membrane
positive regulation of protein targeting to membrane
positive regulation of cell motility
positive regulation of glucose import in response to insulin stimulus
cellular protein modification process
apoptotic process
signal transduction
peptidyl-serine phosphorylation
regulation of cell migration
intracellular signal transduction
fat cell differentiation
mammary gland epithelial cell differentiation
regulation of cell cycle arrest
activation of GTPase activity
