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产品信息
PA5-21553
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 211 and 587 of ALAS-E (Uniprot ID#P22557)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152669
产品详细信息
Recommended positive controls: Raji, K562, HL60, mouse liver.
Predicted reactivity: Mouse (95%), Rat (95%), Zebrafish (80%), Xenopus laevis (81%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ALAS2 specifies an erythroid-specific mitochondrially located enzyme. It catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase 2; ALAS-E; aminolevulinate, delta-, synthase 2; Delta-ALA synthase 2; delta-ALA synthetase; Delta-aminolevulinate synthase 2; erythroid-specific ALAS; PRO2399; RP5-884M20.1
基因别名: ALAS; Alas-2; ALAS-E; ALAS2; ALASE; ANH1; ASB; SIDBA1; XLDPP; XLEPP; XLSA
UniProt ID: (Human) P22557, (Mouse) P08680
Entrez Gene ID: (Human) 212, (Mouse) 11656
response to hypoxia
protoporphyrinogen IX biosynthetic process
heme biosynthetic process
cellular iron ion homeostasis
erythrocyte differentiation
oxygen homeostasis
hemoglobin biosynthetic process
porphyrin-containing compound metabolic process
metabolic process
biosynthetic process
tetrapyrrole biosynthetic process
