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Positive test controls include: Mouse pancreas, Rat pancreas, Rat liver. The target is usually found in the following locations: Mitochondrion.
Immunogen sequence: EPLEIKGAKK PGLVTKNGLV LFGNDGKALT VRNLQFEDGK MIPASQYFST GETSVVELTA EEVKVAETIK VIWAGILSNV PIIEDSTDFF KSGASSMDVA RLVEEIRQKC GGLQLQNEDV YMATKFEGFI QKVVRKLRGE DQEVELVVDY ISKEVNEIMV KMPYQCFING QFTDADDGKT YDTINPTDGS TICKVSYASL A
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 10-formyltetrahydrofolate dehydrogenase ALDH1L2; aldehyde dehydrogenase 1 family, member L2; aldehyde dehydrogenase 1L2; Aldehyde dehydrogenase family 1 member L2; aldehyde dehydrogenase family 1 member L2, mitochondrial; Mitochondrial 10-formyltetrahydrofolate dehydrogenase; Mitochondrial 10-FTHFDH; probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
基因别名: ALDH1L2; D330038I09Rik; mtFDH; RGD1309458
UniProt ID: (Human) Q3SY69, (Mouse) Q8K009
Entrez Gene ID: (Human) 160428, (Rat) 299699, (Mouse) 216188