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Reconstitute in 100 µL of MQ water. Centrifuge to remove any insoluble material.
Specificity of this antibody: ALDH3A1.
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alcohol dehydrogenase family 3, subfamily A1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A1; Aldehyde dehydrogenase, dimeric NADP-preferring; Dioxin-inducible aldehyde dehydrogenase 3; MGC10406
基因别名: Ahd-4; Ahd4; Aldh; Aldh3; Aldh3a1; Aldh4
UniProt ID: (Mouse) P47739
Entrez Gene ID: (Mouse) 11670