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产品信息
PA5-85334
产品规格
种属反应
Bovine,
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human aldehyde dehydrogenase 3A1.
偶联物
形式
Liquid
浓度
0.61 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792476
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (82%), Rat (83%), Dog (91%), Bovine (89%).
Positive Control: mouse eye, Whole Cornea.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50% of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorption of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice; mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alcohol dehydrogenase family 3, subfamily A1; Aldehyde dehydrogenase 3; aldehyde dehydrogenase 3 family, member A1; aldehyde dehydrogenase 3 family, memberA1; aldehyde dehydrogenase 3, stomach cytosolic (class 3); Aldehyde dehydrogenase 4; Aldehyde dehydrogenase family 3 member A1; aldehyde dehydrogenase isozyme 3; aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; BCP54; corneal 15.8 kDa protein; corneal protein 54, transparentin; dehydrogenase 3, dimeric NAPD-prefering; Dioxin-inducible aldehyde dehydrogenase 3; MGC10406; stomach aldehyde dehydrogenase; transparentin
基因别名: Ahd-4; Ahd4; Aldh; ALDH3; ALDH3A1; Aldh4; ALDHIII
UniProt ID: (Human) P30838, (Mouse) P47739
Entrez Gene ID: (Human) 218, (Bovine) 281617, (Mouse) 11670
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
aldehyde dehydrogenase [NAD(P)+] activity
protein binding
alcohol dehydrogenase (NADP+) activity
benzaldehyde dehydrogenase (NAD+) activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
dehydrogenase
