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产品信息
MA5-25891
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI7H6
抗原
Full length human recombinant protein of ALOX15 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2722849
靶标信息
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 12-LOX; 12/15-lipoxygenase; 12/15-LO; 12/15-LOX; 15-lipooxygenase-1; 15-LOX; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15
基因别名: 12-LO; 12-LOX; 12/15-LO; 15-LOX; 15-LOX-1; 15LOX-1; Alox12; Alox12l; ALOX15; L-12LO; LOG15
UniProt ID: (Human) P16050, (Mouse) P39654, (Rat) Q02759
Entrez Gene ID: (Human) 246, (Mouse) 11687, (Rat) 81639
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
hepoxilin-epoxide hydrolase activity
arachidonate 15-lipoxygenase activity
hepoxilin A3 synthase activity
eoxin A4 synthase activity
lipid binding
oxidoreductase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
metal ion binding
dioxygenase activity
potassium channel inhibitor activity
oxygenase
ossification
negative regulation of adaptive immune response
phosphatidylethanolamine biosynthetic process
leukotriene metabolic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
bone mineralization
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
apoptotic cell clearance
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process
lipid metabolic process
fatty acid metabolic process
positive regulation of cell proliferation
fatty acid oxidation
positive regulation of cell growth
regulation of membrane potential
negative regulation of apoptotic process
negative regulation of cell volume
icosanoid biosynthetic process
