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MA5-17030 targets ALPL in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17030 immunogen is purified recombinant fragment of human ALPL expressed in E. Coli.
MA5-17030 detects ALPL which has a predicted molecular weight of approximately 57.3kDa.
Alkaline phosphatase is a homodimeric protein enzyme (86 kDa), containing two zinc atoms crucial to its catalytic function per monomer, and it is optimally active at alkaline pH environments. The enzyme is found in prokaryotes and eukaryotes, with the same general function but in different structural forms suitable to organism's environment. ALP plays a role in liver metabolism and development within the skeleton. In bacteria, ALP acts as a source of inorganic phosphate. In yeast, ALP can be a useful protein for studying membrane protein sorting.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alkaline phosphatase liver/bone/kidney isozyme; Alkaline phosphatase, tissue-nonspecific isozyme; AP-TNAP; FLJ40094; FLJ93059; glycerophosphatase; liver/bone/kidney-type alkaline phosphatase; MGC161443; MGC167935; Phosphoamidase; Phosphocreatine phosphatase; tissue-nonspecific ALP
基因别名: ALPL; AP-TNAP; APTNAP; HOPS; TNAP; TNSALP
UniProt ID: (Human) P05186
Entrez Gene ID: (Human) 249