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AMPD3 Antibody (PA5-103597) in ICC/IF
Immunocytochemistry analysis of AMPD3 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with AMPD3 polyclonal antibody (Product # PA5-103597) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
产品信息
PA5-103597
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human AMPD3(Accession Q01432), corresponding to amino acid residues H514-A564.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2852933
产品详细信息
Antibody detects endogenous levels of total AMPD3.
靶标信息
AMPD3 is a member of the AMP deaminase gene family. This protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. The protein is the erythrocyte (E) isoforms, whereas other family members isoforms predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adenosine monophosphate deaminase (isoform E); AMP aminohydrolase; AMP deaminase 3; AMP deaminase H-type; AMP deaminase isoform E; Ampd; Erythrocyte AMP deaminase; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; Heart-type AMPD; myoadenylate deaminase
基因别名: AMPD3
UniProt ID: (Human) Q01432, (Rat) O09178, (Mouse) O08739
Entrez Gene ID: (Human) 272, (Rat) 25095, (Mouse) 11717
AMP catabolic process
IMP salvage
erythrocyte homeostasis
purine-containing compound salvage
ADP metabolic process
ATP metabolic process
GTP metabolic process
energy homeostasis
IMP biosynthetic process
AMP metabolic process
nucleotide metabolic process
purine ribonucleoside monophosphate biosynthetic process
