Invitrogen

ANGPTL3 Polyclonal Antibody

ANGPTL3 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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ANGPTL3 Antibody (PA5-47127) in IHC (F)

Immunohistochemical analysis of ANGPTL3 in perfusion fixed frozen sections of mouse liver. Samples were incubated in ANGPTL3 polyclonal antibody (Product # PA5-47127) using a dilution of 5 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm of hepatocytes.

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产品信息

PA5-47127

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.25 µg/mL

免疫组化（冰冻） (IHC (F))

5-15 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Sf 21-derived recombinant mouse Angiopoietin-like Protein 3/ANGPTL3 Ser17-Thr455

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2576792

产品详细信息

In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) Angiopoietin-1, rhAngiopoietin-2, recombinant mouse Angiopoietin-3, rhAngiopoietin-4, and rhAngiopoietin-like factor/CDT6 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2.

仅用于科研。不用于诊断过程。未经明确授权不得转售。