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This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization) have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AIDA-1; amyloid-beta precursor protein intracellular domain associated protein 1; Amyloid-beta protein intracellular domain-associated protein 1; Ankyrin repeat and sterile alpha motif domain-containing protein 1B; cajalin 2; E2A-PBX1-associated protein; EB-1; MGC26087
基因别名: AIDA; AIDA-1; ANKS1B; ANKS2; cajalin-2; EB-1; EB1
UniProt ID: (Human) Q7Z6G8
Entrez Gene ID: (Human) 56899