Invitrogen

ANO6 Polyclonal Antibody

View all (7) ANO6 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-88322

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 750-830 of human ANO6 (NP_0010205272)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.92 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804828

Product Specific Information

Immunogen sequence: IPRLVYYWSF SVPPYGDHTS YTMEGYINNT LSIFKVADFK NKSKGNPYSD LGNHTTCRYR DFRYPPGHPQ EYKHNIYYWH V; Positive Samples: A-549, Mouse liver, Rat brain; Cellular Location: Cell membrane, Multi-pass membrane protein

Target Information

May act as a calcium-activated chloride channel.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F

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Gene Aliases: 2900059G15Rik; AA407480; ANO6; AW554778; BDPLT7; F730003B03Rik; SCTS; TMEM16F

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UniProt ID: (Human) Q4KMQ2, (Mouse) Q6P9J9

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Entrez Gene ID: (Human) 196527, (Rat) 315272, (Mouse) 105722

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Function(s)
calcium activated cation channel activity intracellular calcium activated chloride channel activity voltage-gated ion channel activity voltage-gated chloride channel activity protein binding phospholipid scramblase activity protein homodimerization activity molecular_function chloride channel activity
Process(es)
dendritic cell chemotaxis activation of blood coagulation via clotting cascade cation transport chloride transport blood coagulation phospholipid transport phospholipid scrambling bone mineralization involved in bone maturation regulation of anion transport calcium activated phospholipid scrambling calcium activated phosphatidylserine scrambling calcium activated phosphatidylcholine scrambling calcium activated galactosylceramide scrambling phosphatidylserine exposure on apoptotic cell surface phosphatidylserine exposure on blood platelet cation transmembrane transport positive regulation of potassium ion export chloride transmembrane transport positive regulation of endothelial cell apoptotic process lipid transport positive regulation of bone mineralization bleb assembly ion transmembrane transport positive regulation of ion transmembrane transport purinergic nucleotide receptor signaling pathway sodium ion transmembrane transport positive regulation of apoptotic process negative regulation of cell volume pore complex assembly positive regulation of phagocytosis, engulfment calcium ion transmembrane transport positive regulation of monocyte chemotaxis regulation of anion transmembrane transport transport ion transport regulation of ion transmembrane transport
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