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AP3B1 is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Structurally, AP3B1 is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in AP3B1 are associated with Hermansky-Pudlak syndrome type 2.
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蛋白别名: Adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3, beta 1 subunit; Adaptor-related protein complex 3 subunit beta-1; adaptor-related protein complex 3, beta 1 subunit; AP-3 complex beta-3A subunit; AP-3 complex subunit beta-1; ap3; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain
基因别名: ADTB3; ADTB3A; AP3B1; HPS; HPS2; PE
UniProt ID: (Human) O00203
Entrez Gene ID: (Human) 8546