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AP3B1 Antibody (PA5-106298) in IHC (P)
Immunohistochemistry analysis of AP3B1 in rat stomach tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with AP3B1 polyclonal antibody (Product # PA5-106298) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-106298
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human AP3B1(Accession O00203), corresponding to amino acid residues I936-V986.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2853975
产品详细信息
Antibody detects endogenous levels of total AP3B1.
靶标信息
AP3B1 is a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Structurally, AP3B1 is part of the heterotetrameric AP-3 protein complex which interacts with the scaffolding protein clathrin. Mutations in AP3B1 are associated with Hermansky-Pudlak syndrome type 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adapter-related protein complex 3 subunit beta-1; adaptor protein complex AP-3 beta-1 subunit; Adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3, beta 1 subunit; Adaptor-related protein complex 3 subunit beta-1; adaptor-related protein complex 3, beta 1 subunit; adaptor-related protein complex AP-3, beta 1 subunit; AP-3 complex beta-3A subunit; AP-3 complex subunit beta-1; ap3; Beta-3A-adaptin; beta3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain; recombination induced mutation 2
基因别名: ADTB3; ADTB3A; AP-3; AP3B1; AU015684; beta3A; C78395; HPS; HPS2; PE; pearl; rim2
UniProt ID: (Human) O00203, (Mouse) Q9Z1T1
Entrez Gene ID: (Human) 8546, (Mouse) 11774, (Rat) 309969
protein targeting to lysosome
intracellular protein transport
blood coagulation
anterograde axonal transport
melanosome organization
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
anterograde synaptic vesicle transport
positive regulation of NK T cell differentiation
transport
zinc II ion transport
protein transport
vesicle-mediated transport
antigen processing and presentation
biological_process
